Hypertrophic Cardiomyopathy Study

Approximately 2750 participants will be enrolled in this study from 35-40 sites in North America and Europe. Participation in this study will require 1 study visit that will take about 3 hours (over 2 days if necessary), and telephone calls once per year for up to 5 years to gather health history information. Each telephone call will take up to an hour. Those who agree to participate will go through a screening period to make sure they are eligible to participate. During the screening period, participants will have the following tests and procedures (includes, but is not limited to): review of medical history, physical exam and vital signs, standard blood tests to test for kidney function and a urine pregnancy test, questionnaire to determine if they are claustrophobic, blood draws to measure blood counts, blood proteins, and genetic testing, electrocardiogram if one has not been done within the past year, echocardiography (ultrasound of the heart) if one has not been done within the past year, and cardiac MRI. Participants will then be followed by telephone call for up to 5 years. Keeping in touch with participants helps the researchers understand the relationship between the MRI and blood test findings.