Description
All participants on this study must have been enrolled on AREN03B2. There are three arms to this study. Participants will receive nephrectomy and observation only; or chemotherapy alone; or chemotherapy with radiation therapy. Most participants will have had total resection of the kidney and tumor. Patients with unresectable or incompletely resected tumors will receive chemotherapy and be re-evaluated following 2 cycles (approximately 6 weeks). If the tumor is determined to be resectable, further surgery will be performed.
Eligibility
Inclusion Criteria
- Less than 30 years of age
- Diagnosed with a Stage 1-III diagnosis of Wilms' Tumor
- Must have an appropriate performance level
- No prior directed Chemotherapy or Radiation Therapy
- Must have adequate organ function
- Cannot become pregnant or breastfeed
- Sexually active patients must agree to use adequate birth control