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- Kidney, Pancreas and Liver Transplants
- Become a Living Donor
There is a severe shortage of transplant-eligible kidneys. As a result, kidney transplant candidates are waiting years to receive a new kidney, which is time many candidates can’t afford. However, living kidney donors are saving lives by helping people with kidney failure get a new kidney faster. Whether it’s a family member, friend or complete stranger as the recipient, by becoming a living donor you have the opportunity to help someone waiting for a kidney.
The benefits of living donation
Research shows that organs from living donors generally work better, last longer and are available sooner – which is why Lehigh Valley Institute for Surgical Excellence is committed to connecting patients with living donors whenever possible.
There are many benefits associated with living kidney donation. In comparison to kidneys from deceased donors, kidneys from living donors:
- Result in significantly better long-term survival, lasting nearly twice as long as kidneys from deceased donors.
- Decrease a candidate’s wait time – a person could spend five years or more on the waiting list for a deceased donor while a living donor transplant can be done within a matter of months.
- Usually start functioning immediately after transplant, which leads to quicker recovery after transplant.
- Produce better results with half the risk for kidney failure in the first year.
- Are more convenient, allowing you to schedule the donation for a time that works well for both the donor and the recipient.
Who can be a living kidney donor?
To be a living donor, you must be between 18-75 years of age, in good physical and mental health and have normal kidney function. Potential donors are thoroughly screened to make sure it is safe for them to be a donor. There are some medical conditions that could prevent you from being a living donor, including:
- Uncontrolled high blood pressure
- Diabetes
- Cancer
- HIV
- Hepatitis
- Acute infections
- Having a serious mental health condition that requires treatment
How to become a living kidney donor
All potential kidney donors should fill out Lehigh Valley Health Network’s (LVHN) Opens in new tab living donor form. You will then undergo an extensive evaluation process, which serves to protect you (the donor) and to help ensure the success of the transplant.
Designed to determine whether donors are healthy enough to donate, our transplant evaluation process involves:
- Psychological evaluation: At Lehigh Valley Institute for Surgical Excellence, we are committed to ensuring each donor is in good mental health and understands the donation process. During this evaluation, our transplant team will fully explain the living donation process to ensure you are making an informed decision. This evaluation is also done to certify there is no pressure from friends or family to donate, no promise of financial incentive and that you have realistic expectations. It also provides you with an opportunity to express yourself more authentically than you might be able to with family or the recipient present.
- Medical tests: To ensure you are healthy enough to donate, there will be some medical tests performed. You’ll be asked about your medical history to find out if you have or had any conditions that would prevent you from donating. Following this initial screen are a blood test to find out whether you are compatible with the recipient and a physical exam to make sure you are healthy enough to donate. This blood sample is taken not only to check for compatibility between you and the recipient, but also to check for any viral activity or transmissible diseases (such as HIV/AIDS, hepatitis, cancer or others), glucose intolerance and electrolyte imbalance and to assess your kidney function.
Your test results will be sent to LVHN’s transplant team, which will review them carefully to determine your physical health and suitability as a donor. If you are a suitable candidate for living donation and you decide to go ahead with it, an operation will be scheduled. The final decision to proceed will be a group decision among you, your recipient and the transplant team.
Frequently asked questions
Most people are born with two healthy kidneys, and only one is required to live. Potential living donors are thoroughly screened to make sure it is safe for them to be a donor. There are also benefits to living donation:
- Planning a surgery time that is convenient for both of you.
- Recovery time for you may be shorter.
- Kidneys from living donors often result in better outcomes.
You should let friends and family know about your transplant needs. People receiving a kidney from a living donor have better outcomes than those receiving one from a deceased donor. Living donors must be between 18-75 years of age and in good health.
Not everyone who needs a transplant is medically suitable to have a living donor kidney. They may have a complicated medical or surgical history or be too high of a risk. More than half of LVHN transplants are from a deceased donor.
What if I don't have a living donor? Will I still be on the list?
Yes, the waiting list is for candidates waiting for a kidney from a deceased donor. A deceased donor is someone who has died, usually from a severe brain injury.
Are all deceased donors the same?
No, every donor is different: Different ages, genders, ethnicities, some with prior diabetes or high blood pressure, each with different levels of kidney function. Much of this information is summarized in the Kidney Donor Prognostic Index (KDPI). The KDPI scale is in a percent from one, the best donor, to 100, not a good donor. We only offer kidneys from donors with KDPI greater than 85 percent to those who have agreed to receive offers from these donors.
Will you tell me anything about the donor?
We are obligated to keep the donor anonymous, so there is very little information we can share with you. However, when you get called with an organ offer, if you have consented to receive offers of KDPI greater than 85 percent donors, we will tell you which category the donor falls into, KDPI less than 85 percent or greater than 85 percent. Most high KDPI donor kidneys will have a biopsy performed to look for how well we hope the kidney will function, and we will share this biopsy result with you.
I have heard about people accepting organs from donors who have done IV drugs or who overdosed. Is this true?
Yes, this is true. In general, illicit drugs, while they have lots of bad effects, do not damage the kidneys or impair kidney function. Medically, our concern for donors who use illicit drugs is the risk of the donor kidney transmitting a viral infection like hepatitis to a transplant recipient.
For any organ offer, we will tell you if the donor meets so-called risk criteria, meaning that the donor has engaged in some type of behavior that increases the donor's chance of acquiring a viral infection. All donors are tested by a very sensitive test for many infections including hepatitis B, hepatitis C, HIV and COVID. You'll be told of any test that is not completely negative, and what the test result means.
The risk of acquiring a viral infection from a transplant is very, very low, but can never be zero. For the riskiest type of donor, which is a donor who died after injecting drugs intravenously, the risk of acquiring a viral infection is less than 1 in 1000. However, all donors carry a risk of disease transmission. Viruses, bacterial infections and cancers have been transmitted to recipients. These are rare events, and more importantly, the risk of dying on the wait list is much higher than contracting a disease from the donor.
We encourage any donor who is not a match for their intended recipient to be enrolled in the kidney exchange program. A kidney exchange program matches donors with appropriate recipients. If you want to be a donor but know you are not a match for the person you wish to donate to, we will find you a match for your kidney and in exchange we find a donor who matches your intended recipient.
Kidney and Pancreas Transplant
The science and practice of organ transplantation surgery can transform lives. When an organ such as the kidney or pancreas stops working on its own, transplant surgery can allow you to live a fuller life, on your terms.
Learn more